We invite applications for a Postdoctoral Research Associate in the Computational Modelling of Ocular Drug Retention and Delivery to work with Professors Eamonn Gaffney and Philip Maini at the Mathematical Institute, and Dr Antonello Caruso at F. Hoffmann-La Roche, on a project modelling ocular drug retention and delivery. This is a full time position, fixed-term for 24 months, and is funded by a research grant from F. Hoffmann-La Roche. The post-holder will be based at the Wolfson Centre for Mathematical Biology (WCMB) at the Mathematical Institute, University of Oxford, with occasional travel to F. Hoffmann-La Roche in Basel, Switzerland.

Ophthalmology drug development is a rapidly growing area aiming to fulfil the unmet medical need for durable and more efficacious treatments. In turn, this motivates the supervisors’ continuing development of a rational and quantitative mechanism-based computational modelling framework for understanding ocular drug retention and concomitant drug levels within the target site of the retina. This project will advance this modelling programme, and further areas of development include taking into account finer grained spatial heterogeneity within the eye, the incorporation of novel drug designs, together with prospective ocular drug retention technologies and integrating the models with Bayesian inference for comparisons with data. The successful candidate will write up their results for publication, present papers at conferences, contribute ideas for new research projects, and organise activities relevant to the WCMB, alongside managing their own academic research and administrative activities.

Applicants will be expected to have, or be close to completing, a PhD in mathematical biology, applied mathematics, scientific computing, physiological modelling or a related discipline. They will also possess sufficient specialist knowledge to work within the established research programme, and have excellent communication skills.

Please direct informal enquiries to the Recruitment Coordinator (email: vacancies@maths.ox.ac.uk), quoting vacancy reference 149153.

Please note that applicants will be selected for interview purely based on their ability to satisfy the selection criteria as outlined in the attached job description. You will be required to upload a statement setting out how you meet the selection criteria, a curriculum vitae including full list of publications, a statement of research interests, and the contact details of two referees as part of your online application. (NOTE: Applicants are responsible for contacting their referees and making sure that their letters are received by the closing date).

To apply for this vacancy and for further information, including a job description and selection criteria, please follow the link below:

https://my.corehr.com/pls/uoxrecruit/erq_jobspec_details_form.jobspec?p_id=149153

Only applications received before 12.00 noon UK time on Monday 22 February 2021 can be considered. Interviews are anticipated to take place in mid to late March 2021.

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